Abstract: Qiaokou Oilfield locates at the center of Dongpu sag, and is attributed to the typical heterogeneous oil reservoir.Because of a serious areal and vertical heterogeneity and difficulties of water drive in low-permeability layers, Qiaokou Oilfield enters in the high water-containing period too early and water drive oill recovery factor is low. Aiming at the serious heterogeneity and low oil recovery factor, utilize large displacement directional well technology to dispose adjusting wells on the plane to solve serious areal heterogeneity; combine the adjustment of liquid production system (mainly through water plugging and reserve fracture reconstruction) with the adjustment of water injection stucture to reduce vertical heterogeneity and realize shifts among layers. The implementation shows that contradiction between oil reservoir planes and layers alleviate progressively and oil recovery factor rises. It also offers experience to improve the oil recovery factor in the similar oilfields.