Abstract: Based on the reservoir characteristics and sensibility analysis of Weizhou11-1-A1 well, alcohol-base acid is used in accordance with the practical condition of pay zone in the offshore oilfield. The com-pound acid has less damage and better suitable dissolving capacity to formation. It has remarkable effects on plug removing induced by drilling fluid and cement liquid. The alcohol-base acid for Weizhou11-1-A1 well is developed after experiment of selecting the type, concentration of acid and additives and analyzing reacted acid.