Abstract: The buried hill reservoirs in Beibu Gulf Basin are primarily composed of limestone with well-developed fractures and vugs, posing a significant risk of lost circulation. After circulation loss occurs, wellbore cleaning becomes constrained and wellbore stability maintenance changes, leading to a sharp increase in the probability of pipe sticking. The rapid reduction in the equivalent circulating density of the annulus fluid column further exacerbates the severe problem of lost circulation and kick occurring in the same hydrocarbon-active reservoir interval, greatly increases the difficulty of ensuring well control safety. To address these challenges encountered during the drilling of buried hill reservoirs, the adaptive solidization and plugging method was applied to resolve severe lost circulation issues. A deep integration of geology and engineering was implemented to accurately set the technical casing shoe at the reservoir entry point. Managed pressure drilling equipment, combined with drilling with seawater under a dynamic mud cap, was utilized to reach the target depth. Ultimately, no recordable safety, environmental or quality incidents occurred, successfully achieving the objective of safe drilling in the buried hill reservoirs. This provides valuable experience and a strong reference for the safe drilling of similar formations in the future.