Abstract: The overall buckling phenomenon of submarine pipelines is becoming more and more prominent due to the high-temperature and high-pressure environment in deep sea. To control the overall buckling of pipelines and avoid large structural deformation and damage, this study took a deep-sea submarine pipeline as research object, conducted a full-scale experiment on the overall buckling of submarine pipelines, and explored the failure modes of the overall buckling of the pipeline. At the same time, a finite element calculation model for the overall buckling of submarine pipelines based on vertical disturbance technology was established by using ABAQUS software, and sensitivity analysis of multiple parameters (sleeper height, pipeline lateral displacement, double sleeper spacing) was conducted. The research results indicate that the critical buckling load of pipelines gradually decreases with the increase of sleeper height and lateral displacement of pipelines, and gradually increases with the increase of pipeline wall thickness. For double sleeper structures, the critical buckling load of pipelines gradually decreases with the increase of spacing between sleepers. However, the support height of the sleepers and the spacing between the double sleepers cannot be increased indefinitely, and the optimal parameters need to be determined in conjunction with pipeline suspension analysis. This study can provide reference for the research on vertical buckling control of deepwater submarine pipelines.