Abstract: Yingqiong Basin is one of the three largest overpressure basins with rich oil and gas resources potential in the world. The overpressure mechanism is very complicated in the basin, and the distribution of overpressure is very extensive. The highest pressure coefficient in drilled wells is as high as 2.36. It is indicated by the previous drilling operations that the abnormal formation pressure has been seriously affecting the safety and efficiency of drilling and completion operation, and has always been a key factor that restricts natural gas exploration and development with high temperature and high pressure and deep water. Firstly, the development of formation pressure prediction technology has been reviewed in detail in the paper. Secondly, challenges of formation pressure prediction technology in Yingqiong Basin are summarized, and the key factors restricting the accuracy of formation pressure prediction technology are also revealed. In view of the safety requirements of the future exploration and drilling operation, the development trend and key research direction of formation pressure prediction technology in the basin have been pointed out finally, which can provide an important reference for the pressure prediction in offshore low-degree exploration areas.