Abstract: Through studying the distribution and characteristics of Paleogene fault systems and main syndepositional faults in Qingdong Depression, faults developed in Qingdong area can be divided into three different types according to their strikes:NNE, EW, and NW. Fault 1 of qingdong in NNE direction and fault f1, f2 in EW direction controlled the division of secondary tectonic units. Qingdong depression can be divided into northern sub-depression, northern bulge, middle sub-depression, southern bulge, southern sub-depression, south-western gentle slope and the eastern actic region from north to south. Studies indicates that subsidence centers of different depressions experienced obviously migration in Paleogene, which was controlled by the differential activity and evolution of main syndepositional faults. Continuing activity of f1 and f3 controlled the depositional filling of the northern deep depression, f1 and f4 controlled development of middle sub-depression and southern sub-depression respectively. Activity and assemble style of main faults controlled the development of coarse-clastic depositional systems, such as sublacustrine fan, fan delta and braided delta. Fault zone formed by syndepositional faults adjacent to oil generating depression have favorable conditions for formation of sandstone reservoirs, and the eastern basin marginal fault zone was the most favorable zone.