Abstract: Now there are kinds of developmental plug-up agents, but very effective superplastic generic plugup agent is rare, so we put emphasis on it. We apply routine experimental method to do some laboratory test on superplastic polymer gel genera plug-up agent.Laboratory appraisements prove plug-up agent can successfully do injection profile modification plug-up amidst mid-high temperature (91℃), and the effect is so fine. DH1-5-6 well of the Talimu oil field depended on water flood recovery at the initial stage of production, in the near future the water or moisture hoiking resulted in sharp output decline and the daily oil output decreased from 200t to 67t. After inject plug-up agent ZAY, output apparently increase and daily oil output increases by 13%.