Abstract: The perforated completion of horizontal wells has been used widely at home and abroad. The optimization perforating parameters are critical for economic and high-efficiency production of horizontal wells. The optimization design models are established for perforating parameters of horizontal wells based on the orthogonal test method, and 9 important factors are selected, meanwhile the influence of various factors on the horizontal well productivity is analyzed. Perforated completion parameters scheme is optimized. The study provided a new method and technical support for perforating parameter optimization of horizontal wells.