Abstract: During hot water flooding development process,scale deposit phenomenon become serious with rising in temperature,traditional scale inhibitor is not efficient.Through radical polymerization in lab,a kind of low cost and high temperature tolerance quadripolymer scale inhibitor system has been developed.The analytical results of FTTR indicate that scale inhibitor polymer contains carboxyl,phosphonyl and sulphonate groups.The laboratory experiment results indicated that good scale inhibiting effect to CaCO_3and CaSO_4 have been obtained,and the scale inhibiting rate is 96.74%and 96.91%respectively in the test condition of 60 mg/L mass concentration,95℃ temperature and 12 h.This scale inhibitor has great application prospect in hot water flooding in low permeability and super low permeability reservoirs.